Waaaay off topic now! heheh
Yes of course systems can be isolated and locked out - it's usually only a case of pulling the right circuit breakers, but that can generate more time reading up on the system finding which circuit breakers to pull. This in turn generates more paperwork because everything that is touched on the aircraft must be written into the record of maintenance - this is so that come a shift change etc those circuit breakers are reset when the final check through the paperwork is carried out.
The other issue is that quite often the circuit breakers can be miles away at the other end of a big jet and often behind more panels - more time spent finding which panels to take off; more tools needed; more paperwork needed; another set of steps needed..etc etc. Not something you want to be doing for a five minute job.
So placarding the cockpit is easier.
A placard also tells aircrew that someone is working on the aircraft.
When the crew get out to the aircraft if they find nobody is there (because the engineer has gone for a tea-break or more tools), the aircrew see no placard, so assume the aircraft is not being worked on, they could possibly reset the system themselves and start doing their stuff, then fail to put the aircraft back into the same condition they found it in (circuit breakers) - and when the techie gets back, something unexpected happens and an accident takes place.
Dropping a tool or nut/bolt/washer is a different matter, all instances must be investigated (paperwork raised) to recover the FOD.
Many times when looking for a lost washer or similar item, Ive found all manner of other items that we didnt know were there, from paint brushes to tools, sunglasses, pens, a teaspoon, and even an ancient Mars Bar.
They didnt like doing it much but on fast jets, if a lost article wasnt found, the crews were sometimes asked to do inverted flights and 'jink' around while inverted. They'd be given a little bag to put all the 'bits' into. Hopefully the lost bit would drop into the canopy, but there were many times when it never did.